Pharmacology PhD candidate and biology expert with hands-on disease-modeling experience, multi-omics bioinformatics training, and AI4S/AIDD-relevant research. Author of 12+ peer-reviewed publications (169+ citations, h-index 5, IF up to 14.6). Experienced in designing rigorous experiments, interpreting omics data, and writing clear, high-depth biological reasoning for AI model evaluation.
Key Qualifications
Advanced biology problem design and review
R / Python multi-omics workflows
Genetics, transcriptomics, pathway reasoning
AI4S/AIDD ML and virtual-cell literacy
Controls, confounders, reproducibility
Fluent English scientific communication
Research Experience
Graduate Researcher
2022 - Present
Sun Yat-sen University · School of Pharmaceutical Sciences
- Formulated complex biological research questions in pharmacology, molecular mechanisms, omics interpretation, experimental design, and translational drug discovery.
- Applied multi-omics bioinformatics analysis to map cell-type-specific injury mechanisms in cardiovascular disease models using R/Python-based workflows.
- Interpreted transcriptomic, pathway, and phenotype evidence to connect molecular mechanisms with disease progression, target hypotheses, and experimental validation.
- Advanced AIDD-relevant therapeutic research on cryptotanshinone derivative DST-3, linking compound design, MD/docking-aware hypotheses, and in-vivo validation.
- Designed rigorous wet-lab studies with attention to controls, confounders, blinding, reproducibility, dose-response logic, and data interpretation.
- Reviewed and communicated scientific evidence through manuscripts, data summaries, and clear expert-level explanations for cross-domain collaborators.
Selected Publications
- Zhang J, Dai Y (co-first), Yu J, Chen Y, et al. "SNX3 exacerbates hepatic fibrosis by amplifying TGF-β1/Smad signaling pathway in hepatocyte-HSC fibrotic loop." Acta Pharmaceutica Sinica B (2026). IF 14.6 Co-1st Cited: 0
- Su L, Mo R, Dai Y, Wang Z, et al. "Xueshuantong injection alleviates ischemic heart failure via targeting PFKP-mediated endothelial-to-mesenchymal transition." Phytomedicine, 158085 (2026). IF 11.3 Co-1st Cited: 1
- Dai Y, Yu J, He G, et al. "DST-3 attenuates glutamate excitotoxicity after ischemic stroke via CREB-Homer1 axis activation." Phytomedicine 147, 157223 (2025). IF 11.3 1st Author Cited: 2
- Dai Y, Yang W, Song H, et al. "Long-term effects of e-cigarette aerosol on cardiovascular and pulmonary systems: A comparative study to cigarette smoke." Environment International 185, 108521 (2024). IF 10.2 1st Author Cited: 25
- Dai Y, Duan K, Huang G, et al. "E-cigarette inhalation effects on lung function and inflammation in mice." Frontiers in Toxicology 5, 1232040 (2023). IF 5.1 1st Author Cited: 13
Additional JCR-Q1 work spans biotechnology, medicinal chemistry, neuroprotection, pulmonary fibrosis, public health, and drug discovery.
Open Source
XSTARS
Active Development
Open-source Excel add-in for automated statistics, data quality checks, and publication-quality figures for bench researchers; built through AI-assisted, rapid research-tool development. VBA / Python Stars 14